Pyrroloquinoline quinone
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(Redirected from PQQ)
Pyrroloquinoline quinone, originally discovered in 1979, was reported to be a vitamin in mice on April 24 2003 by a research team led by Takafumi Kato of the Japanese Institute of Physical and Chemical Research (source). Because it has not been shown that any disease results from a dietary deficiency of this substance in humans, it is not considered a vitamin in humans.
The conclusions of Kato et al - that PQQ is a vitamin - have been strongly challenged; these challenges have been published in Nature where the first 'New Vitamin' claim was first made:
- Role of PQQ as a mammalian enzyme cofactor? [Leigh M. Felton, Chris Anthony School of Biological Sciences, University of Southampton, Southampton SO16 7PX, UK e-mail: c.anthony@soton.ac.uk doi:10.1038/nature03322]
- Is pyrroloquinoline quinone a vitamin? [Robert Rucker*, David Storms*, Annemarie Sheets*, Eskouhie Tchaparian*,Andrea Fascetti† Departments of *Nutrition, College of Agriculture and Environmental Sciences, and †Molecular Bioscience, School of Veterinary Medicine, University of California, Davis, California 95616, USA e-mail: rbrucker@ucdavis.edu doi:10.1038/nature03323]