Salivary gland

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The salivary glands produce saliva, which keeps the mouth and other parts of the digestive system moist. It also helps break down carbohydrates (with salivary amylase, formerly known as ptyalin) and lubricates the passage of food down from the oro-pharynx to the esophagus to the stomach.

There are three main pairs of salivary glands: the parotid, the submandibular and the sublingual glands. There are also many small glands in the tongue, cheeks, lips and palate, all of which consist entirely of mucous secreting cells (see Histology below) except for the serous glands of von Ebner, which reside within the moats surrounding the circumvallate papillae in the posterior 1/3 of the tongue, anterior to the terminal sulcus.

1 Histology
2 Location of the glands
3 Role in disease
4 Diagnostic investigation
5 External links

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Histology

Two types of epithelial cells in salivary glands produce either mucous or serous secretions. The parotid gland produces serous secretions. The submandibular and submaxillary glands contain a mixture of both types of cells, and produce a mixture of the two liquids.

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Location of the glands

There are three salivary glands:

The parotid gland is located near the ear (par- = next to, -otid = ear), and is the largest of the salivary glands.
The sublingual gland lies underneath the tongue.
The submandibular gland is a U-shaped structure, and lies beneath the ramus of the mandible (the angle of the chin).

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Role in disease

See mumps (parotiditis epidemica) and Sjögren syndrome.

Salivary duct calculus may cause blockage of the ducts, causing pain and swelling of the gland.

Tumors of the salivary glands may occur. These are usually benign, but may be malignant. The most common type of benign tumor is Pleomorphic adenoma, followed by Warthin's tumor.

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