Barry Marshall
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Barry J. Marshall, MBBS (born 30 September 1951 in Kalgoorlie, Western Australia) is an Australian physician and Professor of Clinical Microbiology at the University of Western Australia. He is well-known for proving that the bacteria Helicobacter pylori is the cause of most stomach ulcers, reversing decades of medical doctrine which held that ulcers were caused by stress, spicy foods, and too much acid.
Professor Marshall (Medicine and Pharmacology) completed his undergraduate medical degree at UWA in 1974. He met Robin Warren, a pathologist interested in gastritis, during internal medicine fellowship training at Royal Perth Hospital in 1981. Together, the pair studied the presence of spiral bacteria in association with gastritis. The following year (1982), they performed the initial culture of H. pylori and developed their hypothesis related to the bacterial cause of peptic ulcer and gastric cancer.
The H. pylori theory was ridiculed by the establishment scientists and doctors, who did not believe that any bacteria could live in the acidic stomach. To force people to pay attention to this theory, Marshall drank a petri-dish of the bacteria and soon developed gastritis. The bacteria disappeared after two weeks and the illness resolved spontaneously with the aid of antibiotics. In 1984, while at Fremantle Hospital, Professor Marshall fulfilled Koch's postulates for H. pylori and gastritis. Following that, he did research at the University of Virginia, USA, before returning to Australia in 1997. He held a Burnet Fellowship at the University of Western Australia from 1998-2003 [1].
In 2005, the Karolinska Institute in Stockholm awarded the Nobel Prize in Physiology or Medicine to Dr. Marshall and his long-time collaborator Dr. Warren "for their discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease". Professor Marshall continues research related to H. pylori and runs a molecular biology lab at UWA.
Other awards
- Albert Lasker Award for Clinical Medical Research in 1995
- Gairdner Foundation International Award in 1996
- Nobel Prize in Physiology or Medicine in 2005
- List of additional awards
When Barry Marshall was twenty-one he was a state yo-yo champion.
References
- Marshall BJ. Unidentified curved bacillus on gastric epithelium in active chronic gastritis. Lancet 1983;1((8336):1273-1275. PMID 6134060.
- Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach patients with gastritis and peptic ulceration. Lancet 1984;1(8390):1311-1315. PMID 6145023.
- http://www.vianet.net.au/~bjmrshll/features2.html
- http://www.usnews.com/usnews/doubleissue/heroes/marshall.htm
External links
- Helicobacter pylori Research Laboratory
- The Nobel Prize in Physiology or Medicine 2005
- A discussion of the rate of acceptance of Marshall and Warren's work.de:Barry Marshall
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