5-MeO-DMT
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| 5-MeO-DMT | |
|---|---|
| Chemical formula | C13H18N2O |
| Chemical name | 5-Methoxy-N,N-dimethyltryptamine or 5-methoxy-3-[2-(dimethylamino)ethyl]indole |
| Molecular mass | 218.298 g/mol |
| Melting point | 67.7 °C (154 °F) |
| CAS number | 1019-45-0 |
| SMILES | COC1=CC2=C(NC=C2CCN(C)C)C=C1 |
| Image:5-MeO-DMT.png | |
5-MeO-DMT is a very powerful psychedelic tryptamine. It is found in a wide variety of plant and toad species, and like its close relative DMT, it has been used as an entheogen by South American shamans for over 1200 years.
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Chemistry
5-MeO-DMT was first synthesized in 1936, and in 1959 it was isolated as one of the psychoactive ingredients of Anadenanthera peregrina seeds used in Yopo snuff.
History
Traditionally 5-MeO-DMT has been used as a psychedelic snuff, such as Yopo or Vilca, and may be a trace constituent of ayahuasca when plants such as Diplopterys cabrerana are used as an admixture. 5-MeO-DMT is also found in the venom of the Colorado River toad (Bufo alvarius), although there is no direct evidence this was used as a hallucinogen until recent times.
Use and effects
When used as a drug in its purified form, 5-MeO-DMT is smoked, snorted, or injected and is active at a dose of as little as 2mg. 5-MeO-DMT is also active orally, when taken with an monoamine oxidase inhibitor, but according to numerous reports, the combination with MAOI is extremely unpleasant and has a strong bodyload. According to the researcher Jonathan Ott, 5-MeO-DMT is active orally with doses over 30mg without aid of an MAOI.
The onset of effects occurs in seconds after smoking/injecting, or minutes after insufflating, and the experience is sometimes described as similar to a near-death experience. Peak effects last for approximately 5-10 minutes, when smoked. When insufflated, the peak effects are considerably less intense, but last for 15-25 minutes on average.
External links
| Psychedelic tryptamines edit |
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4-Acetoxy-DET | 4-Acetoxy-DIPT | α-ET | α-MT | Baeocystin | Bufotenin | DET | DIPT | DMT | DPT | EIPT | Ethocin | Iprocin | MET | MIPT |5-MeO-α-ET | 5-MeO-α-MT | 5-MeO-DALT | 5-MeO-DET | 5-MeO-DIPT | 5-MeO-DMT | 5-MeO-DPT | 5-MeO-MIPT | Miprocin | Norbaeocystin | Psilocin | Psilocybin | |