Mescaline
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Mescaline | |
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Chemical name | 3,4,5-Trimethoxy- phenethylamine or 2-(3,4,5-trimethoxyphenyl) ethanamine |
Chemical formula | C11H17NO3 |
Molecular mass | 211.26 g/mol |
Melting point | 128–129 °C |
CAS numbers | 54-04-6 |
SMILES | NCCC1=CC(OC)=C(OC)C(OC)=C1 |
Image:Mescaline structure.png |
Mescaline or 3,4,5-trimethoxyphenethylamine is a psychedelic hallucinogenic drug and entheogen of the phenethylamine family. It is either synthesized (as mescaline sulfate) or extracted from the peyote cactus (Lophophora williamsii), the San Pedro cactus (Echinopsis pachanoi), or the Peruvian Torch cactus (Echinopsis peruviana). It is also found in a number of other members of the Cactaceae.
The use of extract from peyote in Native American religious ceremonies has been noted since the earliest European contact, notably by the Huichols in Mexico. It was first isolated and identified in 1897 by the German Arthur Heffter and first synthesized in 1919. The effective human dosage is 200–400 milligrams (3.75 mg/kg), with the effects lasting for up to twelve hours. It is not physically addictive. In the US it was made illegal in 1970 by the Comprehensive Drug Abuse Prevention and Control Act. It was prohibited internationally by the 1971 Convention on Psychotropic Substances[1] and is categorised as a Schedule I hallucinogen by the CSA. Users typically experience visual hallucinations and radically altered states of consciousness, often experienced as pleasurable and illuminating but occasionally as accompanied by feelings of anxiety or revulsion.
Contents |
Chemistry
Mescaline can be synthesized, usually starting from 3,4,5-trimethoxybenzaldehyde (PiHKAL entry).
Side effects
One or more of the following side effects may or may not accompany any individual experience with mescaline.
Positive Side Effects
- Open eye visuals
- Closed-eye visuals
- New thought processes
- Dream-like scenarios
- Euphoria
- Mystical experience
Neutral Side Effects
- Pupil dilation
- Sensations of warm and cold
- Temporary splitting/destruction of ego
Negative Side Effects
- Dizziness
- Vomiting
- Tachycardia
- Diarrhea
- Headaches
- Anxiety
- Feeling of dying or annihilation
- Fear of not being able to return to normal consciousness
- Hallucinogen persisting perception disorder (HPPD)
- Irrationality of the thought-process
Famous Users
- Aldous Huxley
- Ernst Jünger [2]
- Leo Kenney [3]
- Henri Michaux [4]
- Jim Morrison
- Carlos Santana
- Hunter S. Thompson
- Robert Del Naja
- Timothy Leary
- Christopher Mayhew, reporter for BBC Panorama, took Mescaline Hydrochloride while being filmed in 1955 in a suppressed report
- Jean-Paul Sartre
- Antonin Artaud
See also
External links
- Mescaline at Erowid
- PiHKAL entry
- Mescaline: The Chemistry and Pharmacology of its Analogs Essay by Alexander Shulgin
Categorization
Template:Hallucinogenic phenethylaminesda:Meskalin de:Meskalin es:Mescalina fi:Meskaliini fr:Mescaline he:מסקלין io:Meskalino it:Mescalina ja:メスカリン nl:Mescaline pl:Meskalina pt:Mescalina ru:Мескалин sk:Meskalín sv:Meskalin