Cefazolin
From Free net encyclopedia
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[[Image:{{{image|Cefazolin.png}}}|{{{width|220}}}px|Cefazolin chemical structure]] | |
| 3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-([2-(tetrazol-1-yl)acetyl]amino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate IUPAC name | |
| CAS number [1] | }}} |
| PubChem 2617 | DrugBank [2] |
| Chemical formula | C14H13N8O4S3- |
| Molecular weight | 453.503 |
| Bioavailability | ? |
| Metabolism | ? |
| Elimination half-life | ? |
| Excretion | ? |
| Pregnancy category | ? |
| Legal status | Unscheduled |
| Routes of administration | I.V. |
Cefazolin, also known as cefazoline or cephazolin, is an antibiotic in the cephalosporin family.
The drug is usually administrated either by intramuscular injection (injection into a large muscle) or intravenous infusion (intravenous fluid into a vein).
Indications
Cefazolin is mainly used to treat bacterial infections of the skin. It can also be used to treat moderately severe bacterial infections involving the lung, bone, joint, stomach, blood, heart valve, and urinary tract. It is effective only against infections caused by staphylococci and streptococci species of bacteria. These organisms are common on normal human skin. Resistance to cefazolin is seen in several species of bacteria.
Side effects
Side effects from cefazolin are not common. Possible side effect includes:
- diarrhea
- stomach pain
- upset stomach
- vomiting
Cefazolin is marketed under the following brand names: Ancef®, Cefacidal®, Cefamezin®, Cefrina®, Elzogram®, Gramaxin®, Kefazol®, Kefol®, Kefzol®, Kefzolan®, Kezolin®, Novaporin®, and Zolicef®