Clone (genetics)

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In genetics, a clone is a replica of all or part of a macromolecule (eg. DNA). Cloning a gene means to extract a gene from one organism (for example by PCR) and insert it into a second organism (usually via a vector), where it can be used and studied.

Cloning a gene sometimes can refer to success in identifying a gene associated with some phenotype. For example, when biologists say that the gene for disease X has been cloned, they mean that the gene's location and DNA sequence has been identified, although the ability to specifically copy the physical DNA is a side-effect of its identification. A related technique called subcloning refers to transferring a gene from one plasmid into another for further study.

One famous example of cloning is Dolly the sheep.

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