Frovatriptan

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Image:Frovatriptan Frova.gif

[[Image:{{{image|Frovatriptan.png}}}|{{{width|220}}}px|Frovatriptan chemical structure]]
Frovatriptan

6-methylamino-6,7,8,9-tetrahydro
-5H-carbazole-3-carboxamide
IUPAC name
CAS number
158930-17-7
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PubChem
5284561
DrugBank
APRD00270
Chemical formula C14H17N3O
Molecular weight 243.304 g/mol
Bioavailability 20-30%
Metabolism Hepatic
Elimination half-life 26 hours
Excretion Renal
Pregnancy category C: (USA)
B3: (AUS)
Legal status Prescription only
Routes of administration Oral


Frovatriptan (Frova®) is a triptan drug developed by Endo Pharmaceuticals for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. It is available as 2.5 mg tablets.

Frovatriptan has mean terminal elimination half-life of approximately 26 hours, which is substantially longer than for other triptans.

Frovatriptan is available only by prescription in the United States.

External links

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Triptans edit

Almotriptan | Eletriptan | Frovatriptan | Naratriptan | Rizatriptan | Sumatriptan | Zolmitriptan

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