Frovatriptan
From Free net encyclopedia
[[Image:{{{image|Frovatriptan.png}}}|{{{width|220}}}px|Frovatriptan chemical structure]] | |
6-methylamino-6,7,8,9-tetrahydro -5H-carbazole-3-carboxamide IUPAC name | |
CAS number 158930-17-7 | }}} |
PubChem 5284561 | DrugBank APRD00270 |
Chemical formula | C14H17N3O |
Molecular weight | 243.304 g/mol |
Bioavailability | 20-30% |
Metabolism | Hepatic |
Elimination half-life | 26 hours |
Excretion | Renal |
Pregnancy category | C: (USA) B3: (AUS) |
Legal status | Prescription only |
Routes of administration | Oral |
Frovatriptan (Frova®) is a triptan drug developed by Endo Pharmaceuticals for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. It is available as 2.5 mg tablets.
Frovatriptan has mean terminal elimination half-life of approximately 26 hours, which is substantially longer than for other triptans.
Frovatriptan is available only by prescription in the United States.
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External links
- Frova (manufacturer's website)
- Frovatriptan (patient information)
Triptans edit |
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Almotriptan | Eletriptan | Frovatriptan | Naratriptan | Rizatriptan | Sumatriptan | Zolmitriptan |