Isosorbide dinitrate

[[Image:{{{image\|Isosorbide dinitrate.png}}}\|{{{width\|220}}}px\|Isosorbide dinitrate chemical structure]] Isosorbide dinitrate
4,8-dinitrooxy-2,6-dioxabicyclo[3.3.0]octane IUPAC name
CAS number 87-33-2	}}}
PubChem 3780	DrugBank APRD00455
Chemical formula	C₆H₈N₂O₈
Molecular weight	236.136 g/mol
Bioavailability	10-90%, average 25%
Metabolism	Hepatic
Elimination half-life	1 hour
Excretion	Renal
Pregnancy category	C: (USA)
Legal status	Prescription only
Routes of administration	Oral

Isosorbide dinitrate is a nitrate used pharmacologically as a vasodilator, e.g. in angina pectoris but also for anal fissure, a condition which is known to involve decreased blood supply leading to poor healing.

Isosorbide dinitrate is a component of BiDil.

Nitrates edit
{Glyceryl trinitrate} {Isosorbide dinitrate} {Isosorbide mononitrate} {Molsidomine} {Pentaerythritol tetranitrate}