Sequence analysis
From Free net encyclopedia
The term "sequence analysis" in biology implies subjecting a DNA or peptide sequence to sequence alignment, sequence databases, repeated sequence searches, or other bioinformatics methods on a computer.
Sequence analysis in molecular biology and bioinformatics is an automated, computer-based examination of characteristical fragments, e.g. of a DNA-strand. It basically includes five biologically relevant topics:
- the comparison of sequences in order to find similar sequences (sequence alignment)
- identification of gene-structures, reading frames, distributions of introns and exons and regulatory elements
- prediction of protein structures
- genome mapping
- comparison of homologous sequences to construct a molecular phylogeny
In chemistry, sequence analysis comprises techniques used to determine the sequence of a polymer formed of several monomers. In molecular biology and genetics, the same process is called simply "sequencing."nl:Sequentieanalyse