Sodium valproate
From Free net encyclopedia
|
Image:Sodium valproate.png | |
| sodium 2-propylpentanoate | |
| CAS number 1069-66-5 | ATC code N03AG01 |
| Chemical formula | C8H15NaO2 |
| Molecular weight | 166.20 |
| Bioavailability | ? |
| Metabolism | ? |
| Elimination half-life | ? |
| Excretion | ? |
| Pregnancy category | D |
| Legal status | ? |
| Routes of administration | Oral, Intravenous |
Sodium valproate (INN) or valproate sodium (USAN) is the sodium salt of valproic acid and is an anticonvulsant used in the treatment of epilepsy. The intravenous formulations are used when oral administration is not possible. Epilim is a popular anticonvulsant in the UK. Sodium valproate may also be used as an antidepressant, though this is not its usual indication.
Contents |
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Formulations
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US
- Intravenous injection – Depacon® by Abbott Laboratories.
- Syrup – Depakene by Abbott Laboratories. (Note Depakene tablets are valproic acid).
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UK & Australia
- Tablets – Orlept® by Wockhardt and Epilim® by Sanofi-Aventis.
- Oral solution – Orlept® Sugar Free by Wockhardt and Epilim® by Sanofi-Aventis.
- Syrup – Epilim® by Sanofi-Aventis.
- Intravenous injection – Epilim® Intravenous by Sanofi-Aventis.
- Extended release tablets – Epilim Chrono® by Sanofi-Aventis. A combination of sodium valproate and valproic acid in a 2.3:1 ratio.
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Germany, Switzerland, Norway
- Tablets – Orfiril® by Desitin Pharmaceuticals
- Intravenous injection – Orfiril® IV by Desitin Pharmaceuticals
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South Africa
- Syrup – Convulex® by Byk Madaus
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Canada
- Intravenous injection – Epival® or Epiject® by Abbott Laboratories.
- Syrup – Depakene® by Abbott Laboratories. Generic formulations include Apo-Valproic and ratio-Valproic.
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Others
In much of Europe, Depakine® and Depakine Chrono® are equivalent to Epilim and Epilim Chrono above.
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See also
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