TSM

TSM can stand for:

Taiwan Semiconductor Manufacturing Company, a semiconductor foundry, headquartered in Taiwan.
Target Setting Mode, a method of sweeping mines.
Transportation System Management, an alternative used for comparison when analyzing whether or not to build new roadways or mass transit links, such as busways, metros, and light rail lines. It is often compared with a No-Build approach.

IBM Tivoli Storage Manager (formerly known as ADSM), an Enterprise backup software product from IBM.